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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK7
All Species:
13.64
Human Site:
S545
Identified Species:
23.08
UniProt:
Q8WTQ7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTQ7
NP_631948.1
553
62212
S545
G
C
E
E
G
N
S
S
K
S
G
V
C
L
L
Chimpanzee
Pan troglodytes
XP_526333
553
62171
S545
G
C
G
E
G
N
S
S
K
S
G
V
C
L
L
Rhesus Macaque
Macaca mulatta
XP_001112570
553
62224
S545
G
C
G
E
G
N
S
S
K
S
G
V
C
L
L
Dog
Lupus familis
XP_542813
553
62196
S545
G
C
G
D
G
N
S
S
K
S
G
V
C
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEB1
590
67714
R539
T
L
S
P
D
L
N
R
S
Q
P
P
E
P
P
Rat
Rattus norvegicus
Q62833
590
67764
R539
T
L
S
P
D
L
N
R
S
Q
P
P
E
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
D546
Q
K
P
D
D
M
R
D
G
P
G
E
D
E
T
Chicken
Gallus gallus
XP_426681
551
62925
G541
S
G
G
Y
A
N
G
G
E
A
K
S
G
V
C
Frog
Xenopus laevis
NP_001131051
551
62674
G542
T
G
G
G
G
N
S
G
E
K
S
G
V
C
S
Zebra Danio
Brachydanio rerio
NP_001027011
549
62214
D540
S
S
G
G
S
D
D
D
K
K
S
G
T
C
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
I667
C
P
T
P
D
L
Q
I
N
A
A
P
E
P
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
R570
G
N
V
M
W
N
L
R
P
D
G
I
N
M
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42818
465
52569
L458
V
R
P
P
P
S
F
L
H
Q
S
T
T
T
L
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
S803
K
N
M
N
N
S
H
S
Q
M
D
F
D
G
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.9
85.7
N.A.
41.8
42.2
N.A.
47.9
72.8
68.7
60.2
N.A.
38.2
N.A.
39.4
N.A.
Protein Similarity:
100
99.4
98
92.7
N.A.
60.6
60.6
N.A.
65.8
84.2
82.8
75.9
N.A.
54.3
N.A.
57.6
N.A.
P-Site Identity:
100
93.3
93.3
86.6
N.A.
0
0
N.A.
6.6
6.6
20
6.6
N.A.
0
N.A.
20
N.A.
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
6.6
6.6
N.A.
13.3
26.6
26.6
13.3
N.A.
6.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.3
38.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
15
8
0
0
0
0
% A
% Cys:
8
29
0
0
0
0
0
0
0
0
0
0
29
15
8
% C
% Asp:
0
0
0
15
29
8
8
15
0
8
8
0
15
0
22
% D
% Glu:
0
0
8
22
0
0
0
0
15
0
0
8
22
8
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
36
15
43
15
36
0
8
15
8
0
43
15
8
8
0
% G
% His:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% I
% Lys:
8
8
0
0
0
0
0
0
36
15
8
0
0
0
0
% K
% Leu:
0
15
0
0
0
22
8
8
0
0
0
0
0
29
36
% L
% Met:
0
0
8
8
0
8
0
0
0
8
0
0
0
8
0
% M
% Asn:
0
15
0
8
8
50
15
0
8
0
0
0
8
0
0
% N
% Pro:
0
8
15
29
8
0
0
0
8
8
15
22
0
22
15
% P
% Gln:
8
0
0
0
0
0
8
0
8
22
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
8
22
0
0
0
0
0
0
0
% R
% Ser:
15
8
15
0
8
15
36
36
15
29
22
8
0
0
8
% S
% Thr:
22
0
8
0
0
0
0
0
0
0
0
8
15
8
15
% T
% Val:
8
0
8
0
0
0
0
0
0
0
0
29
8
8
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _